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Láser y luz pulsada intensa en el tratamiento de hemangiomas infantiles y malformaciones vasculares

机译:激光和强脉冲光治疗儿童血管瘤和血管畸形

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摘要

The use of the indications of the laser in treatingvascular malformations and infantile haemangiomas isbased on the theory of selective photothermolysis, inwhich the oxyhaemoglobin is the target chromophoreon which the light of the laser acts, thus avoiding damageto neighbouring tissues. The pulsed dye laser is themost employed and at present is the treatment ofchoice in capillary malformations (port-wine stains). Avariable response is obtained, with a substantial clearingof the colour of the lesion after several sessions.Application at early ages seems to improve the results.Venous malformations, especially those localised inthe mucosa, respond better to the Nd:YAG laser; lymphaticmalformations to the CO2 laser. Arteriovenousmalformations rarely respond. Use of the pulsed dyelaser in the phase of proliferation of the haemangiomasis subject to controversy, except where there is ulceration.A rapid re-epithelialization is obtained in thesecases following its use. In the involution phase,patients with residual vascular lesions can benefit fromother lasers such as KTP or Nd:YAG. If they show anatrophic surface and scars these complicationsimprove with the CO2 laser or Er:YAG. New treatmentmodalities are emerging, such as photodynamic therapy,whose efficacy and safety, both in the treatment ofhaemangiomas and vascular malformations, have yetto be confirmed.
机译:激光适应症用于治疗血管畸形和婴儿性血管瘤的方法是基于选择性光热解理论,其中氧合血红蛋白是激光的光起作用的目标发色团,从而避免了对邻近组织的损害。脉冲染料激光是最常用的方法,目前是对毛细血管畸形(Port-wine酒渍)的选择。经过几次治疗后,获得了可变的反应,并明显清除了病灶的颜色。早期应用似乎可以改善结果。静脉畸形,尤其是位于粘膜的畸形,对Nd:YAG激光的反应更好;淋巴畸形的二氧化碳激光。动静脉畸形很少反应。脉冲染料激光在有争议的血血管瘤增生阶段的使用,除非有溃疡。在这些情况下,使用后可快速重新上皮。在对合阶段,残留血管病变的患者可以从其他激光(例如KTP或Nd:YAG)中受益。如果它们显示出萎缩的表面并留下疤痕,则使用CO2激光或Er:YAG可以改善这些并发症。新的治疗方式正在出现,例如光动力疗法,其功效和安全性在治疗血管瘤和血管畸形方面均尚未得到证实。

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